By Donald Y.M. Leung, Malcolm W. Greaves
This state-of-the-science reference offers invaluable details at the pathophysiology and monetary and social effects of allergic epidermis reactions, in addition to new remedies according to rising ideas of dermis disorder pathobiology-addressing the epidemiology, mechanisms, occupational results, environmental triggers, and quality-of-life issues. makes a speciality of atopic dermatitis, urticaria, and allergic touch dermatitis, between different more and more universal pores and skin issues. Written by way of greater than 35 top researchers, Allergic epidermis illness ·reviews uncomplicated ideas of the motives of allergic dermis responses ·analyzes the function of key phone varieties, effector molecules, cytokines, mediators, chemokines, phone adhesion molecules, and immunogenetic mechanisms ·showcases the dynamics of adhesion molecules and the pathophysiology of pruritus ·examines medical gains of epidermis asthma, quite relating to immune mechanisms that be sure pathogenic path and final result ·investigates behaviors of keratinocytes, dendritic cells and macrophages, fibroblasts, lymphocytes, granulocytes, and endothelial cells ·explores phototherapy, photochemotherapy, immunomodulatory remedy, and standard antiinflammatory treatment for recalcitrant epidermis ailments ·discusses anaphylaxis and different allergy symptoms to insect bites ·surveys demographism, vibratory angioedema, and different different types of urticaria ·identifies allergic and infectious triggers of pores and skin ailment ·and extra! Containing over 1800 bibliographic citations, Allergic dermis disorder is a must-read source for dermatologists, allergists, immunologists, pharmaceutical and beauty chemists, internists, pediatricians, and graduate and scientific tuition scholars in those disciplines.
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Additional info for Allergic skin disease: a multidisciplinary approach
61. Tan BB, Weald D, Strickland I, Friedman PS. Double-blind controlled trial of effect of housedust-mite allergen avoidance on atopic dermatitis. Lancet 1996; 347:15–18. 62. Olesen AB, Ellingsen AR, Olesen H, Juul S, Thestrup-Pedersen K. Atopic dermatitis and birth factors: Historical follow up by record linkage. Br Med J 1997; 314:1003–1008. 63. Black PN, Sharpe S. Dietary fat and asthma: Is there a connection? Eur Respir J 1997; 10: 6–12. 64. Traupe H, Menge G, Kandt I, Karmaus W. Higher frequency of atopic dermatitis and decrease in viral warts among children exposed to chemicals liberated in a chemical accident in Frankfurt, Germany.
Helv Paediatr Acta 1984; 39:129–136. 31. Schultz Larsen F, Holm NV, Henningsen K. Atopic dermatitis. A genetic-epidemiologic study in a population-based twin sample. J Am Acad Dermatol 1986; 15:487–494. 32. Burr ML, Butland BK, King S, Vaughan-Williams E. Changes in asthma prevalence: two surveys 15 years apart. Arch Dis Child 1989; 64:1452–1456. 33. Ninan TK, Russell G. Respiratory symptoms and atopy in Aberdeen school children: Evidence from two surveys 25 years apart. Br Med J 1992; 304:873–875.
6 million people, insurance companies paid compensation rates of $3 million a year from 1991 through 1995. Comparable spending in the United States would cost, conservatively, $160 million [104,105]. These amounts represent the tip of the iceberg of health-care costs related to allergic contact dermatitis. IV. PHOTODERMATITIS/PHOTOALLERGY Abnormal response to ultraviolet radiation includes polymorphous light eruption in which sunlight is thought to induce a neoantigen and a subsequent delayed hypersensitivity reac- Page 10 tion by continuous light exposure (see Chap.
Allergic skin disease: a multidisciplinary approach by Donald Y.M. Leung, Malcolm W. Greaves