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Acute Leukemias VII: Experimental Approaches and Novel - download pdf or read online

By J. Thomale, M. R. Müller, C. Buschfort, S. Seeber, M. F. Rajewsky (auth.), Prof. Dr. W. Hiddemann, Prof. Dr. T. Büchner, Prof. Doz. Dr. B. Wörmann, Prof. Dr. J. Ritter, Prof. Doz. Dr. U. Creutzig, M. Keating MD PhD, W. Plunkett MD PhD (eds.)

ISBN-10: 3642719600

ISBN-13: 9783642719608

ISBN-10: 3642719627

ISBN-13: 9783642719622

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Extra info for Acute Leukemias VII: Experimental Approaches and Novel Therapies

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Of a case with leukemia-initiating blasts in SCID-mice from a patient with CD34-/ CD38+ blasts differs from that conclusion. However, analysis of the immunophenotype of this leukemic sample shows that it has to be classified into aberrant acquisition of CD38. According to our results in a large group of patients with newly diagnosed AML, presented in this paper, this group of leukemias is rare and accounts for only 2% of all samples. The function of CD34 has not been fully elucidated (Krause et al.

2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. Neidle S, Waring M (1993) Molecular aspects of anticancer drug-DNA interactions. In: Neidle S, Fuller W, Cohen JS (eds) Topics in molecular and structural biology, Macmillan, London Friedberg EC, Walker GC, Siede W (1995) DNA repair and mutagenesis. ASM Press, Washington Chaney SG, Sancar S (1996) DNA repair: enzymatic mechanisms and relevance to drug response. J. Natl. Cancer Inst 88:l346-l360 Genetic instability in cancer (1996). ) Cancer surveys, Vol.

1994). The observation by Terpstra et al. of a case with leukemia-initiating blasts in SCID-mice from a patient with CD34-/ CD38+ blasts differs from that conclusion. However, analysis of the immunophenotype of this leukemic sample shows that it has to be classified into aberrant acquisition of CD38. According to our results in a large group of patients with newly diagnosed AML, presented in this paper, this group of leukemias is rare and accounts for only 2% of all samples. The function of CD34 has not been fully elucidated (Krause et al.

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Acute Leukemias VII: Experimental Approaches and Novel Therapies by J. Thomale, M. R. Müller, C. Buschfort, S. Seeber, M. F. Rajewsky (auth.), Prof. Dr. W. Hiddemann, Prof. Dr. T. Büchner, Prof. Doz. Dr. B. Wörmann, Prof. Dr. J. Ritter, Prof. Doz. Dr. U. Creutzig, M. Keating MD PhD, W. Plunkett MD PhD (eds.)


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